【摘要】 目的　探讨妥塞敏用于早孕妇女行人工流产负压吸引术的止血效果。方法　 12 0例早孕妇女分为妥塞敏组和对照组。每组 6 0例 ,对两组妇女按妇科检查及B超测定判断孕周大小进行配对。两组妇女年龄、停经天数、孕次、宫腔大小、血红蛋白及血小板计数比较 ,差异无显著性 (P>0 0 5 ) ,具有可比性。妥塞敏组妇女在负压吸引术前 30min静脉推注妥塞敏 1g +5 %葡萄糖 2 0ml,5min推注完毕。对照组妇女在负压吸引术前 30min静脉推注 5 %葡萄糖 2 0ml,5min推注完毕。观察两组妇女的术中、术后 30min出血量及副反应。结果　 (1)妥塞敏组出血量 (5 1 6± 17 2 )ml,对照组出血量 (6 3 3± 17 1)ml,两组比较 ,差异有显著性 (P <0 0 5 )。 (2 )妥塞敏组妇女在用药过程中有 18例 (30 0 % )出现轻度恶心 ,8例 (13 0 % )轻度头晕。对照组仅 1例有轻度恶心 ,余无副反应 ,两组妇女均未做任何处理自行好转。结论　妥塞敏用于早孕妇女负压吸引术 ,有较好的止血效果 ,术中及术后出血量均明显减少 ,无严重不良副反应 ,有利于患者的恢复更多还原

【Abstract】 Objective To confirm the decreasing bleeding effect of transamin on the induced abortion for the early pregnancy with more than two months Methods A total of 120 women are divided into two groups (60 pairs) based on the pelvic examination and the size of embryo measured by B ultrasound Those women in the treated group ( n =60) were administed Transamin 1 g/20 ml (iv for 5 minutes) 30 minutes before operation;control group ( n =60) were given 5% glucose and saline 20 ml (iv for 5 minutes) 30 minutes before operation Results There wasn′t any singnificant difference ( P >0 05) between the two groups in the patient′s age, pregnancy age, parities, the cavity volume of uterine, hemoglobin and blood platelet count The bleeding volume was (51 6±17 2) ml for the treated group and (63 3±17 1) ml for the control group ( P <0 05) Conclusions Transamin has effective hemostasis during the induced abortion for the early pregnancy with >2 months It could decrease the volume of bleeding during the operation and benefit for patients recovering更多还原