【摘要】 目的　探讨身体锻炼配合抗骨吸收剂在治疗绝经后骨质疏松症中的作用。方法　对照、动态检查腰椎、左右髋部骨密度 (BMD)变化率及四肢和脊柱骨折发生率。结果　主动进行身体运动和缺乏运动的妇女BMD均显著升高 ,尤以新近运动者 1年内升高最明显 ,达 6 76 %～ 9 79% (P<0 0 5 ) ,1年后常年运动组、新近运动组和缺乏运动组的BMD增长率无显著意义的差别 (P <0 0 5 ) ;常年运动组和新近运动组的第 2年骨折率低于缺乏运动的病人。结论　身体锻炼配合抗骨吸收剂治疗绝经后骨质疏松症时 ,以新近运动者BMD增长最快 ,常年运动组骨折率最低更多还原

【Abstract】 Objective\ To investigate the effects of exercise combined with alendronate on postmenopausal osteoporosis. Methods\ 136 postmenopausal osteoporosis women treated with alendronate were divided into 3 groups: group A practising exercise regularly, group B doing it recently, and group C never doing it. In all subjects bone mineral deusity (BMD) of lumbar spine and hip was measured by DEXA, and the changes in BMD and fracture rates of axial and peripheral bones were observed and compared between the three gruops. Results\ BMD increased significantly in all the three groups esp ecially in group B in the first year, whose BMD increased by 6\^76%～9\^79%( P <0 05).The rates of changes in BMD between the 3 gruops were not significant.Compared with group C, the rates of osteoporotic fracture in groups A and B in the second year were low. Conclusion\ When postmenopausal osteoporosis is managed with active exercise and bone resorption inhibitor, the percentage of increase in BMD is the highest in new exercisers and the fracture rate is the lowest in the habitual exercisers.更多还原