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146例地高辛血药浓度监测分析
The analysis of serum digoxin concentration monitoring of 146 cases
【摘要】 目的 :对我院 1998年 8月~ 2 0 0 0年 8月两年来地高辛血药浓度监测进行分析。方法 :应用放射免疫法测定血药浓度 ,0 .5~ 2 .0ng·ml-1为有效治疗浓度范围。结果 :监测例数共 146例 ,低于 0 .5ng·ml-1的 13例 ,高于 2 .0ng·ml-114例 ,在0 .5~ 2 .0ng·ml-1的 119例次。结论 :影响地高辛血药浓度及中毒的因素是多样的、复杂的 ,提示对地高辛进行血药浓度监测是必要的。
【Abstract】 OBJECTIVE To analyse the results of serum digoxin concentration(SDC) from Aug.1998 to Aug. 2000 in Qingdao Hiserve Hospital.METHODS The digoxin concentration was determined by radioimmunoassay. The effective theraputic concentration is 0.5 ~ 2.0 ng·ml -1 .RESULTS 146 cases were analyzed. The concentrations in 13 cases were under 0.5 ng·ml -1 , in 14 cases were higher than 2.0 ng·ml -1 and in 119 cases were between 0.5 ~ 2.0 ng·ml -1 .CONCLUSIONS The influence of SDC and digoxin intoxication is complex. It was important to monitor the serum digoxin concentration.
【Key words】 digoxin; radioimmunoassay; serum concentration; intoxincation;
- 【文献出处】 中国医院药学杂志 ,Chinese Journal of Hospital Pharmacy , 编辑部邮箱 ,2002年01期
- 【分类号】R969
- 【被引频次】13
- 【下载频次】81