【摘要】 目的 :探讨阻塞性睡眠呼吸暂停综合征 (OSAS)患者的左心功能与呼吸功能变化、肥胖的关系。方法 :选择 30例男性OSAS患者 ,行呼吸和左心功能、血气检查 ,之后用多导睡眠呼吸监测仪进行监测。结果 :OSAS患者呼吸和左心功能的相关分析提示PaO2 与左心室收缩末期内径相关 (r =0 .4 72 ,P<0 .0 1)。将患者按BMI <2 8和 >32分为两组 ,发现BMI高者低通气指数 (HI)和Dd明显升高 ,而PaO2 和睡眠时最低血氧饱和度 (minSaO2 )则显著降低 (P均 <0 .0 5 )。结论 :OSAS患者的HI、Dd、minSaO2 随BMI变化而变化 ,疾病程度越重 ,PaO2 、Dd、min SaO2 越低目的 :探讨阻塞性睡眠呼吸暂停综合征 (OSAS)患者的左心功能与呼吸功能变化、肥胖的关系。方法 :选择 30例男性OSAS患者 ,行呼吸和左心功能、血气检查 ,之后用多导睡眠呼吸监测仪进行监测。结果 :OSAS患者呼吸和左心功能的相关分析提示PaO2 与左心室收缩末期内径相关 (r =0 .4 72 ,P<0 .0 1)。将患者按BMI <2 8和 >32分为两组 ,发现BMI高者低通气指数 (HI)和Dd明显升高 ,而PaO2 和睡眠时最低血氧饱和度 (minSaO2 )则显著降低 (P均 <0 .0 5 )。结论 :OSAS患者的HI、Dd、minSaO2 随BMI变化而变化 ,疾病程度越重 ,PaO2 、Dd、min SaO2 越低更多还原

【Abstract】 Objective: To probe into relations between changes of respiratory, obesity and cardiac function in patients with obstructive sleep apnea syndrome (OSAS) complications in OSAS. Methods: We had measured lung functions, left ventricular functions and blood gases in 30 cases diagnosed as OSAS by polysomnography. Results: With the exception of PaO 2 and end systolic diameter of left ventricle (r=0.472, P<0.01), we could not find any relationships between respiratory and left ventricular function. According to BMI (BMI<28 and >32 respectively), the patients were divided into two groups. The results showed that some parameters such as hypopnea index(HI), Dd, PaO 2 and minimal oxygen saturation(minSaO 2) had the close relation to BMI changes. Conclusion: There were significant differences in BMI, HI, Dd, PaO 2 and minSaO 2, and the severe OSAS, the less Dd, PaO 2 and minSaO 2. These results may be useful in predicting and understanding course of some complications of OSAS patients.更多还原