【摘要】 目的　检测正常儿童彩色图形视觉诱发电位 (CP VEP)的特征 ,以探讨其正常参考值及CP VEP方法学特点。方法　用计算机软件技术 ,PR 65 0分光测色计严格控制亮度和颜色因素 ,采用保留颜色对比、降低亮度对比的方法 ,设置了黑 白、灰 白、红 白、绿 白、红 灰、绿 灰、红 绿七种棋盘格视觉刺激条件 ,对 45例 (90眼 )正常儿童进行CP VEP检测。结果　 (1)正常儿童七种刺激条件下均能记录到稳定的NPN复合波 ,左、右眼P1波潜伏期和振幅比较无显著性差异 (P >0 0 5 )。 (2 )亮度对比联合色觉对比的三种刺激 ,按红 白格、灰 白格、绿 白格顺序 :P1波潜伏期依次为 110 4± 3 9ms、 111 8± 4 8ms、 111 7± 4 2ms ,差异无显著性 ,P1波振幅的比较无统计学差异。(3 )单纯色觉对比的三种刺激 ,按红 灰格、红 绿格、绿 灰格顺序P1波潜伏期依次为 116 1± 5 4ms、119 0± 9 2ms、 13 2 5± 14 9ms ,绿 灰格比红 绿和红 灰格分别延长 12 6ms和 16 4ms ,差异有显著性 ,红 绿格与红 灰格比较无统计学差异 ,P1波振幅的比较无统计学差异。结论　我们的研究将为临床提供正常参考值及方法学参考更多还原

【Abstract】 Objective To investigate the characteristics and methodology of CP VEP in normal children and to provide normative values in clinical application. Methods Seven kinds of reversal checkerbord patterns are simulated, including black white, gray white, red white, green white, red gray, green gray, red green. In our study, CP VEP have been recorded from 45 normal subjects. Results (1) The VEP waveforms between right eye and left eye elicited by seven types of patterns was similar, and there was statistically significant elongation in trial group and significant reduction in amplitude in trial group (P>0 05). (2) The latency of P 1 in red white, gray white, green white pattern are inspectly 110 4±3 9ms, 111 8±4 8ms, 111 7±4 2ms, the difference was not significant (P>0 05). (3) In green gray the latency was significantly longer than that of red green (12 6ms) and red gray (16 4ms) (P<0 05), but there was not statistically significant difference in the amplitude (P>0 05). Conclusions The results provide normative values suitable for clinical application and methodology refence of CP VEP.更多还原