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传染性喉气管炎疫苗免疫对鸡红细胞免疫功能状态的影响

Effect of ILT Vaccination on Red Blood Cell Immune Function in Chicken

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【作者】 李淑芳张继东杨润德李坤武薛宗丽杨淑亚

【Author】 LI Shu_fang 1,ZHANG Ji_dong 1,YANG Run_de 2,LI Kun_wu 3,XUE Zong_li 1,YANG Shu_ya (1.Institute of Hebei Veterinary and Animal Science,Baoding 071000,China; 2.Hebei Agricultural University, Baoding 071000,China; 3.Hebei Normal University, Shijiaz

【机构】 河北省畜牧兽医研究所河北农业大学河北师范大学河北省畜牧兽医研究所 河北保定071000河北保定071000河北石家庄050016河北保定071000

【摘要】 选择健康仔鸡 4 0只 ,随机分为 4组 ,每组 10只。Ⅰ组为健康对照组 ,Ⅱ~Ⅳ组为不同处理的试验组。在 4 5日龄时 ,Ⅱ组免疫传染性喉气管炎 (ILT)疫苗 ,Ⅲ组免疫ILT疫苗同时肌肉注射中药免疫增强剂Ⅰ ,Ⅳ组免疫ILT疫苗同时肌肉注射中药免疫增强剂Ⅱ。分别在免疫前 1天、免疫后第 3天和第 9天 ,测定各组鸡的红细胞免疫功能状态。结果发现 ,试验Ⅱ组的鸡在ILT疫苗免疫后 3天 ,RBC_CR1花环率和RBC_IC花环率显著降低 ,与其他各组比较差异极显著 (P <0 .0 1)。免疫后 9天 ,RBC_CR1花环率和RBC_IC花环率升高到正常水平 ;而Ⅲ组和Ⅳ组 ,免疫后RBC_CR1花环率高于Ⅰ组 (P <0 .0 1、P <0 .0 5 )。说明ILT疫苗免疫会引机体红细胞免疫功能的短暂性降低 ;疫苗免疫的同时使用中药增强剂能够消除红细胞免疫功能短暂性降低的不良反应

【Abstract】 commercial chickens were selected and divided into 4 groups randomly,10 chickens each group.The birds were inoculated with ILT vaccines of the same dose at 45 days of age.Group Ⅰ was set as control;Group Ⅱ was inoculated with vaccine only;group Ⅲ was inoculated with vaccine and injected intramuscularly with Chinese herbal immunopotentiator Ⅰ;Group Ⅳ was done with Chinese herbal Ⅱ along with the vaccination.The immune functions of red blood cells of the birds in different groups were measured at 1 day before.and 3 days,9 days after inoculation respectively.The results indicated that the RBC_CR1 and RBC_IC rosette rates of group Ⅱ decreased at 3 days post immunization,significantly lower than the other groups (p<0.01),and returned to normal level at 9 days post vaccination.Suggested that ILT vaccine can induce transit decrease of RBC immune function.when Chinese herbal immunopotentiator Ⅰ or Ⅱ was applied,the RBC_CR1 and RBC_IC rosette rate was found to be greatly higher than other groups.The result indicated that the Chinese herbal immunopotentiator can enhance the immune function of RBC.

  • 【文献出处】 中国预防兽医学报 ,Chinese Journal of Preventive Veterinary Medicine , 编辑部邮箱 ,2002年03期
  • 【分类号】S858.31
  • 【被引频次】16
  • 【下载频次】98
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