【摘要】 目的 :探讨Alzheimer病 (Alzheimer′sdisease ,AD)患者的记忆缺陷特点及其对功能独立的影响。方法 :采用单盲法对 31例肢体无活动障碍的AD患者分别进行韦氏记忆量表测试和FIM评定 ,分析其记忆缺陷特点及其与FIM的相关性。结果 :31例患者的记忆商数为 2 2 - 89,平均 34,属严重记忆缺陷范围。功能独立检查表 (functionalindependentmeasure,FIM)与记忆商数间呈高度正性直线相关 (r=0 .895 ,P <0 .0 0 1) ;FIM的各分量表得分均与记忆商数MQ有一定的正性直线相关性 ,认知分量表与MQ的相关性最强 (r =0 .895 ,P <0 .0 0 1) ,自理分量表次之 (r =0 .6 72 ,P <0 .0 0 1) ,再次为活动分量表 (r =0 .4 2 9,P <0 .0 5 ) ,括约肌与MQ的相关性最小 (r =0 .373,P <0 .0 5 )。结论 :AD患者的记忆缺陷可对其功能独立性产生影响 ,记忆缺陷越严重功能独立性越差 ,给家庭和社会造成的负担越重更多还原

【Abstract】 Objective: Research for the characteristic of memory function of Alzheimer′s disease (AD) patients and the effect on the functional independent measure(FIM). Method: The patients were assessed with Wechsler′s Memory Scale(WMS) and FIM tests which were separately carried out by two specialists in the same day. Analysis was done to find the characteristic of AD patients and the relationship between memory and FIM. Result: MQ of 31 AD patients were 22-89 which revealed severely damaging. Highly line correlation was found between MQ and FIM ( r = 0.817, P <0.0001). The relativity of cognizing function of FIM to MQ was highest ( r=0.895, P <0.001), self-care to MQ was the next( r = 0.672, P <0.0001) and movement to MQ was the third( r = 0.429, P <0.15), and sphincter function to MQ was the last ( r = 0.373, P <0.05). Conclusion: The memory function of AD patients is severely damaged, and it causes functional independence damage.更多还原