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氟甲砜霉素对鸭大肠杆菌病的药效研究
Efficinecy of Florfenicol in against Experimentally Induced Colibacillosis in Ducks
【摘要】 为了探讨氟甲砜霉素对鸭大肠杆菌病的疗效进行了本研究。用试管2倍稀释法测定氟甲砜霉素及对照药氯霉素对大肠杆菌的最小抑菌浓度,然后用氟甲砜霉素、氯霉素进行混饲给药5d的疗效试验。试验结果表明,氟甲砜霉素、氯霉素对大肠杆菌O78株的最小抑菌浓度分别为6mg/L,8mg/L。100,200,400mg/kg氟甲砜霉素混饲给药对鸭大肠杆菌病的有效率分别为30.3%,93.9%,100%;400mg/kg氯霉素的有效率为93.9%。试验各组之间鸭的增重差异不显著。氟甲砜霉素是新一代的动物专用氯霉素类广谱抗生素,具有较好的抗菌活性,毒副作用小,本试验在应用其对鸭的大肠杆菌病的治疗中,效果显著,并得出适宜剂量。
【Abstract】 The studies dealt with efficacy evaluation of florfenicol against colibacillosis in ducks.In vitro inhibitory tests showed that the MICs of florfenicol,chloramphenicol for E.coli O 78 were6mg /L and8mg /L,Respectively.Following treament with florfenicol at100mg /kg,200mg /kg and400mg /kg via the mixing feed for five successive days,the effec-tive rates for E.coli infected ducks were30.3%,93.9%and100%.When chloramphenicol(400mg /kg)were administered via the mixing feed for five successive days,the effective rates were93.9%.The results showed that the weight gains were not significant among groups.
- 【文献出处】 中国家禽 ,China Poultry , 编辑部邮箱 ,2002年22期
- 【分类号】S858.32
- 【被引频次】18
- 【下载频次】108