【摘要】 目的 :回顾性分析嗅神经母细胞瘤的临床表现、治疗经过及预后。方法 :16例嗅神经母细胞瘤 ,A期4例 ,B期 6例 ,C期 6例。其中单纯放疗或加化疗 6例 ,手术加术后放疗 9例 ,单纯手术 1例。放疗剂量DT4 0Gy～70Gy ,均为常规分割照射。颈部未行预防照射。 结果 :本组病例一、三和五年生存率分别为 75 %、75 %和 6 9%。随访中发现颈部淋巴结转移由初次确诊时的 19%上升至 4 4 % ,再次放疗敏感。结论 :嗅神经母细胞瘤对放疗敏感 ,A期单纯放疗疗效好 ,B、C期宜手术加术后放疗。更多还原

【Abstract】 Purpose:To analyze retrospectively the clinical manifestation, treatment and prognosis. Methods:From 1978 to 1996,16 patients with olfactory neuroblastoma were treated.4 cases were stage A,6 cases were stage B and 6 cases were stage C. Six patients were treated with radiotherapy alone or combined with chemotherapy, 9, with surgery and postoperative radiotherapy and 1,with operative alone. The radiation dosage ranged from 40～70Gy with 2 Gy per day. Results:The 1 , 3 and 5 year survival rates were 75%, 75% and 69%.Conclusions:Olfactory neuroblastoma is sensitivity for radiotherapy, for the patients with stage A, radiotherapy alone is effective for stage B and C olfactory neuroblastoma , combined modality of surgery and postoperative radiotherapy should be the treatment of choice.更多还原