【摘要】 目的　通过对 2个国家级监测点的监测 ,了解贵州省碘缺乏病发展动态 ,探索其影响因素 ,为防治提供依据。方法　按照“碘缺乏病监测方案 (1989)”进行人群甲状腺肿大率调查、盐碘浓度和尿碘水平测定。结果　 2个监测点盐碘浓度从 1989年的 10 .8和 6 .8mg/ kg上升到 1999年的 5 0 .6和 4 6 .2 mg/ kg,尿碘浓度分别从1989年的 87.6和 98.5 μg/ L 上升为 1999年的 2 88.1和 4 2 1.1μg/ L,甲肿率波动在 9.3%～ 18.6 %和 7.7%～2 5 .9%之间 ,并未随碘摄入量的持续增加而不断下降。甲肿率与盐碘和尿碘水平之间 ,无论在 1994年前采用 1/ 5万 KI盐和 1994年以后改用 1/ 2万 KIO3盐 ,相关关系均无显著意义 (P >0 .0 5 )。结论　 1/ 5万碘盐浓度即可满足人群碘缺乏病防治需要。建议以 度甲状腺肿大率作为判定指标更多还原

【Abstract】 Objective To understand the variation of iodine deficiency disorders (IDD) and its effect factors for the reference of prevention and cure.Methods According to "the scheme of IDD surveillance (1989)",the goiter rate (TGR) of children was examined with palpation, and the level of iodized salt and urinary iodine were detected in two surveillance spots.Results In two spots, the level of iodized salt was rising from 10.8 and 6.8 mg/kg in 1989 to 50.6 and 46.2 mg/kg in 1999, the urinary iodine of population was rising from 87.6 and 98.5 μg/L in 1989 to 288.1 and 421.1 μg/L in 1999. The TGR of children was keeping 9.3%~18.6% and 7.7%~25.9% during that time. It was not unceasingly decreased since taking in more and more iodine. No matter taking in 1/50000 KI of salt before 1994 and taking in 1/20000 KIO 3 of salt after 1994, the correlation of TGR with iodized salt and urinary iodine level was not significant (P>0.05).Conclusions The demand of human body for iodine would be gratified with 1/50000 KI salt.It was suggested to use prevalence rate (TGR of Ⅱ°) instead of TGR.更多还原