节点文献
葛根的化学成分研究(英文)
Chemical Constituents of Pueraria peduncularis
【摘要】 目的 从豆科葛属植物云南葛藤 Pueraria peduncularis中分离得到 10个化合物。方法 通过波谱和化学方法分别进行鉴定。结果 它们的化学结构为 :3- O- [β- D-吡喃葡萄糖 (1→ 3) - β- D-吡喃葡萄糖醛酸甲酯苷 ]- 3β,15 α,2 3-三羟基齐墩果 - 12 -烯 - 16 -酮 ( ) ,大豆素 ( ) ,染料木素 ( ) ,大豆苷 ( ) ,染料木苷 ( ) ,3β,15 α-二羟基齐墩果 - 12 -烯 - 16 -酮 ( ) ,羽扇醇 ( ) ,桦木酸 ( ) ,α-菠甾醇葡萄糖苷 ( )和α-菠甾醇 ( )。结论 化合物 对黑曲霉具有抑制活性。
【Abstract】 Object To investigate the chemical constituents from the stem of Pueraria peduncularis (Grah. ex Benth.) Benth. Methods The constituents were isolated on silica gel column chromatography. Their structures were elucidated by chemical and spectroscopic evidence. Results Ten compounds were comfirmed as 3-O-D-glucopyranosyl-(1→3)-β-D-6-O-methyl-glucuronopyranosyl]-3β, 15α, 23-trihydroxy-olean-12-en-16-one (Ⅰ), daidzein (Ⅱ), genistein (Ⅲ), daidzin (Ⅳ), genistin (Ⅴ), 3β, 15α-dihydroxy-olean-12-en-16-one (Ⅵ), lupeol (Ⅶ), betulinic acid (Ⅷ), α-spinasterol-glucopyranoside (Ⅸ) and α-spinasterol (Ⅹ). -3β, 15α, 23-trihydroxy-olean-12-en-16-one (Ⅰ), daidzein (Ⅱ), genistein (Ⅲ), daidzin (Ⅳ), genistin (Ⅴ), 3β, 15α-dihydroxy-olean-12-en-16-one (Ⅵ), lupeol (Ⅶ), betulinic acid (Ⅷ), α-spinasterol-glucopyranoside (Ⅸ) and α-spinasterol (Ⅹ). Conclusion Compound Ⅰ exhibited antimicrobial activity against Aspergillus niger. Compounds Ⅱ~Ⅹ were first isolated from this plant.
【Key words】 Pueraria peduncularis (Grah. ex Benth.) Benth; chemical constituent; Aspergillus niger;
- 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,2002年01期
- 【分类号】R284.1
- 【被引频次】50
- 【下载频次】728