【摘要】 目的 :观察熟地水煎剂 (RGD)、熟地多糖 (RGP)、熟地非多糖 (RGNP)对小鼠外周血象的影响。方法 :实验各组连续灌胃 9天 ,断尾取血测定。各组小鼠于给药第 5天环磷酰胺造模后测定。各组小鼠造模后于 2d、4d、6d、8d分别取血测定。结果 :实验各组对正常小鼠外周血象无组间差异 ,对血虚模型小鼠各给药组与模型组比较 ,RGP与RGD有显著意义 ,RGNP仅对WBC有升高意义。RGP与RGNP均可对抗环磷酰胺所致小鼠WBC下降。但RGP作用优于RGNP。结论 :熟地补血功能具有双向调节作用 ,初步认为 ,熟地多糖为其补血作用有效部位更多还原

【Abstract】 Objective: To investigate the effects of Rehannia glutinosa decoction (RGD)、 Rehmannia glutinosa polysaccharide (RGP) and Rehmannia glutinosa non polysaccharide (RGNP) on peripheral hemogram in mice. Methods: The first experimental group were continuously given RGD、RGP and RGNP for nine days, and then blood sample was taken from tails for determination of peripheral hemogram. The second group were given RGD、RGP and RGNP for five days, after making the blood difficiency model of cyclophosphamide. Determinating peripheral hemogram of the third group, after that those mice were given cyclophosphamide by 2 days, 4 days, 6 days, 8 days. Results: Peripheral hemogram of the every normal group has no difference. To compare the model of blood difficiency group and the control group, there were significant differences, RGNP can only enhance WBC. Both RGP and RGNP can reduce WBC of the mice model of anti cyclophosphamide, while RGP was superior to RGNP. Conclusion: Rehmannia glutinosa has dual directional adjustment function. RGP is tonifying blood active fraction of RG.更多还原