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善得定治疗肠外瘘18例疗效分析

Therapeutic Effect of Saondostatin on 18 Cases with External Intestinal Fistula

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【作者】 瞿彩兴; 马圭; 祁卫东; 陈文; 马维坤;

【Author】 QU Cai xin 1, MA Gui 1, QI Wei dong 1, CHEN Wen 2, MA Wei kun 2( 1.The First Hospiatal of Zhenjiang, Zhenjiang 212003, China; 2. School of Senior Vocational Technology, China Pharmaceutical University, Zhenjiang 212003, China)

【机构】 镇江市第一人民医院; 中国药科大学高等职业技术学院; 中国药科大学高等职业技术学院 江苏镇江212003; 江苏镇江212003; 江苏镇江212003;

【摘要】 [目的 ]对善得定治疗肠外瘘进行疗效分析。 [方法 ]善得定加全肠外营养 (TPN)治疗肠外瘘 18例 ,观察肠液排出量和瘘口闭合情况。 [结果 ]全部病例肠液排出量减少 80 % ;15例病人在治疗 10~ 15天内瘘口自愈 ;1例在治疗过程中反复出现低血糖反应 ,停药后症状消失 ;1例低位结肠瘘者未能自愈转手术治愈 ;1例恶性肿瘤病人患小肠瘘 ,治疗后肠液排出量明显减少。 [结论 ]在加用 TNP的基础上 ,善得定能有效促使肠外瘘瘘口愈合 ,对高位肠瘘的疗效尤为明显。

【Abstract】 To evaluate the therapeutic effect of Sandostatin on external intestinal fistula.Sandostatin was combined with TPN for treatment of 18 cases with external intestinal fistula, where in the output of intestinal juice and healing of fistula were observed. The output of intestinal juice decreased by 80% in all cases. The healing of fistulae in 15 cases was otserved within 10 15 days. The hypoglycemia appeared again and again, then disappeared after withdrawal for one case. Another with low colonic fistula didnt heal and switched into surgery. [CONCLUSION]Combined with TNP , Sandostatin is promotive of healing for external intestinal fistula, especially for high intestinal fistula.

【关键词】 善得定; 肠外瘘; 愈合;
【Key words】 Sandostatin; External intestinal fistula; Healing;
  • 【文献出处】 药学进展 ,Progress In Pharmaceutical Sciences , 编辑部邮箱 ,2002年04期
  • 【分类号】R574
  • 【被引频次】4
  • 【下载频次】26
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