【摘要】 目的　探讨组织型纤溶酶原激活剂 (tissueplasminogenactivator,t-PA)治疗外伤性前房积血继发青光眼的临床效果和安全性。方法　1 6例 (1 6眼 )保守治疗无效的眼挫伤引起的前房积血继发青光眼患者 ,平均眼压 43 1 8mmHg,于伤后 5～ 1 6d前房注入t -PA 1 0 μg。 结果　注药后 72h 1 6例前房积血全部吸收 ,48h眼压全部恢复正常。无并发症出现。结论　前房注射t-PA治疗外伤性前房积血继发青光眼是一安全、有效的方法更多还原

【Abstract】 Objective To investigate the efficacy and safety of tissue plasminogen activatror(t-PA) in the treatment of secondary glaucoma following traumatic hyphema.Methods 16 cases(16 eyes) with uncontrolled glaucoma following traumatic hyphema were observed.The mean IOP was 43.18 mmHg.All cases received intracameral injection of t-PA 10μg at 5 to 16 days after injury.Results In all eyes,the hyphema resolved completely whin 24 to 72 hours and IOP returned to normal range witnin 24 to 48 hours after t-PA injection.Possible side effects were not observed.Conclusion Intracameral t-PA injection is safe and effective in the treatmeat of secondary glaucoma following traumatic hyphema.更多还原