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生物方法制备D-泛酸研究进展
Advances of Several Studies on Producing D-Pantothenic Acid by Bio-technology
【摘要】 概述了生物方法制备D-泛酸的研究情况,主要介绍了发酵葡萄糖生成D-泛解酸,添加β-丙氨酸,直接发酵生产D-泛酸的方法;酶法转化或拆分,特别是不对称还原酮基泛解酸(或内酯),立体选择性水解拆分DL-泛解酸内酯的拆分方法,并对其发展前景进行了评论。
【Abstract】 Advances of several studies on producing D-pantothenic acid by biotechnology were reviewed. The states about preparation of D-Pantothenic acid by fermentation and biotransformation or optical resolution with enzymes were mainly introduced. And their development prospects are also discussed.
【关键词】 D-泛酸;
泛解酸内酯;
酮基泛解酸(或内酯);
发酵;
酶法;
拆分;
【Key words】 D-pantothenic acid; D-pantolactone; Ketopantolactone; Fermentation; Enzyme; Biotransfor-mation; Resolution;
【Key words】 D-pantothenic acid; D-pantolactone; Ketopantolactone; Fermentation; Enzyme; Biotransfor-mation; Resolution;
- 【文献出处】 药物生物技术 ,Pharmaceutical Biotechnology , 编辑部邮箱 ,2002年03期
- 【分类号】TQ465
- 【被引频次】18
- 【下载频次】714