【摘要】 目的 :观察吗丁啉对胃、食管反流相关性支气管哮喘的疗效。方法 :对 5 0例胃、食管反流相关性支气管哮喘患者 ,在支气管哮喘急性发作时给予常规对症治疗的同时 ,给予口服吗丁啉 2 0mg,tid ;伴有慢性胃炎者加服雷米替丁 0 .3g、阿莫西林0 .5g及灭滴灵 0 .2g,tid ;有胃酸过多者夜间加服洛赛克 (losec) 2 0mg。 4wk为一个疗程 ,第一个疗程结束后 ,停药观察 1～ 4wk ,病情复发者继服第二个疗程。结果 :第一个疗程结束后 ,有 45例病人停止发病 ,观察 6mon病情未复发。 5例在停药 1～ 4wk病情复发者 ,继服第二个疗程后 ,有 4例停止发病 ,随访 6mon未复发 ,1例发病次数减少一半。结论 :吗丁啉用以预防和治疗胃、食管反流相关性支气管哮喘具有良好效果更多还原

【Abstract】 AIM:To observe the effect of motilium on bronchial asthma associated with gastroesophageal reflux(GER BA). METHODS:50 cases of GER BA, were treated with routine anti asthma and motilium 20 mg tid,ranitidine 0.3 g,amoxicillin 0.5 g and metronidazolum 0.2 g tid for chronic gastritis cases, and losec 20 mg for the gastric acid rdflux at night. The treatment lasted for 1-4 wk, and then stopped to observe the response of the treatmeat. The recurrent cases would be treated as the above again. RESULTS:45 cases were cured in the 4 wk,no case recrudesced in 6 mon. 5 cases needed another the treatment for 1-4 wk since the recurrence, and 4 of the 5 cases were cured. CONCLUSION: Motilium has a good curative effect in preventing and curing bronchial asthma associated with gastroesophageal reflux.entfor1 -4wksin更多还原