【摘要】 目的　探讨肿瘤坏死因子 -α(TNF -α)在儿童急性病毒性脑炎发病中的作用及意义。方法　对 62例临床确诊为急性病毒性脑炎患儿 (重症 1 7例 ,轻症 45例 )的血清及脑脊液中TNF -α进行检测。结果　急性病毒性脑炎患儿血清、脑脊液中TNF -α较对照组明显升高 ,且重症组患儿明显高于轻症组。结论　病毒性脑炎的发病及病情的轻重与TNF -α密切相关更多还原

【Abstract】 Objective To study the role of tumor necrosis factor-α (TNF-α) in children with acute viral encephalitis. Methods The level of TNF-α in serum and cerebrospinal fluid (CSF) in 62 children with acute viral encephalitis were studied by using ELISA method. Results The levels of TNF-α in serum and CSF were significantly higher in encephalitis children than in normal ones. The levels of TNF-α in severe cases were higher than in mild ones. Conclusion TNF-α is related to the development and seriousness of viral encephalitis.更多还原