【摘要】 目的　评价铅对作业工人子代健康的影响。方法　选择父亲和 (或 )母亲从事铅作业的 14 7名城区儿童 ( 6～10岁 )为接触组 ,父母亲均不接触铅及其它化学毒物的儿童 99名为对照组。测定两组儿童身高、体重、胸围、发铅、血铅、血锌卟啉及智商和部分血液指标。结果　接触组发铅、血铅、血锌卟啉明显高于对照组 (P <0 0 1) ,血红蛋白、红细胞数明显低于对照组 (P <0 0 1) ,女性胸围发育明显落后于对照组 (P <0 0 1) ;上述改变以父亲母亲同时接触铅影响最大、父亲接触铅次之、母亲接触铅影响最小。结论　职业接触铅对子代健康有不良影响更多还原

【Abstract】 Objective To study the effects of parents’ occupational exposure to lead on the health of their descendents. Methods 147 children (6-10 years old) in the city whose father and(or) mother had lead exposure were selected as exposed group, and 99 children, whose parents were without lead and other chemical exposure were served as control group. The height, weight and chest circumstance of descendent were measured; blood and hair lead was assessed by atomic absorption spectrophotometer; zinc porphyrin (ZPP) by fluorometer; intelligence quotient (IQ) was evaluated with Combined Raven’s Test Picture Book (CRT-CC). Results The hair lead, blood lead, blood ZPP, Hb and RBC count of both groups showed significant difference (P<0.01). The development of girl’s chest circumstance seemed to be retarded in exposed group than that in control group (P<0.01). The above change pattern appeared to be mostly marked in those cases with both parents’ exposure, lesser marked with fathers’ exposure only and least marked with mothers’ exposure only. Conclusion Occupational exposure of lead in the parents might have certain adverse effects on the health of their descendents.更多还原