【摘要】 目的　探讨提高接触粉尘工人体内抗超氧阴离子 (O-·2 )能力的方法 ,为寻找尘肺早期诊断的辅助指标及开壁治疗新途径提供依据。方法　检测接尘作业工人血液中超氧化物歧化酶 (SOD)及微量元素 (Cu、Zn、Mn)的含量 ,并对SOD含量下降工人进行治疗观察。结果　检测结果表明 ,接触碳素粉尘及碳黑粉尘工人血液中微量元素铜锌含量有不同程度下降 ,其中锌含量下降较明显 ;接尘工人血液中SOD含量下降 ,其下降幅度与接尘工龄相关不明显 ;接尘工人血液中SOD含量下降者经治疗后有明显提高 (2 4 2 %～ 5 3 3 % )。结论　接尘工人经用微量元素及清除自由基的药物治疗后 ,SOD含量有明显提高 ,为此 ,建议定期给接尘工人补充微量元素 (Cu、Zn)及维生素C、E ,提高他们抗超氧阴离子功能更多还原

【Abstract】 Objective To study the methods of improving the antifransoxygenic anion in the workers exposed to dust. In order to seek an assistant indicator for early diagnosis of pneumoconiosis and provide a new way for treatment. Methods Blood superoxide dismutase(SOD) and microelement(Cu,Zn,Mn) were examined in the dust exposed workers and a therapeutic observation was taken in those with low SOD level. Results The results indicated that the serum microelement Cu level was low and Zn was much lower in the workers exposed to carbon element dust and carbon black dust. The serum SOD level in the exposed workers was low, which showed no significant difference with their length of service. After the treatment, the SOD levels of the low SOD exposed workers could be increased(24.2%-53.3%). Conclusion It is concluded that SOD content can increase obviously through the supplement of microelements and the usage of the drugs that clear the superoxide free radicals in the exposed workers. It is suggested that periodic supplement of microelement(Cu,Zn), vitamin C and Vitamin E are necessary to improve the antifransoxygenic anion in the dust exposed workers.更多还原