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新型2型糖尿病治疗药那格列奈
New hypoglycemic agent nateglinide for non-insulin-dependent diabetes mellitus
【摘要】 那格列奈是一种新型口服降血糖药 ,它通过刺激胰岛素释放而降低血糖 ,与磺酰脲类药物相比 ,本品降血糖作用起效快 ,维持时间短 ,可有效降低餐后血糖水平。本文综述了那格列奈的药理学、毒理学、药动学和临床应用方面的研究进展
【Abstract】 Nateglinide is a novel oral hypoglycemic agent that lowers blood glucose by stimulating insulin release, it exhibits a more rapid onset and shorter duration of hypoglycemic action than the sulphonylureas. It can effectively suppress the postprandial blood excursion. This paper reviews the progress in the pharmacology, toxicology, pharmacokinetics and clinical studies of nateglinide.
【关键词】 那格列奈;
糖尿病,非胰岛素依赖型;
降血糖药;
药理学;
毒理学;
药动学;
【Key words】 nateglinide; diabetes mellitus non insulin dependent; hypoglycemic agents; pharmacology; toxicology; pharmacokinetics;
【Key words】 nateglinide; diabetes mellitus non insulin dependent; hypoglycemic agents; pharmacology; toxicology; pharmacokinetics;
- 【文献出处】 中国新药与临床杂志 ,Chinese Journal of New Drugs and Clinical Remedies , 编辑部邮箱 ,2002年01期
- 【分类号】R977.15
- 【被引频次】51
- 【下载频次】366