【摘要】 目的 :分析橄榄桥脑小脑萎缩 (OPCA)的临床和MR表现。方法 :回顾 2 8例临床拟诊为OPCA并经MR证实的病例 ,所有病人均采用 1.5TMR进行检查 ,获得自旋回波序列T1加权矢状面和T2 、T2 及质子密度加权横断面图像。结果 :小脑半球 2 8例、桥脑腹侧 2 8例、小脑中脚 2 8例和延髓腹侧上部 2 6例体积缩小。在T2 和质子密度加权像上常可见桥横纤维 (19/ 2 8)和小脑中脚 (12 / 2 8)高信号。中脑及幕上亦可见到某些异常征象。结论 :OPCA的MR表现主要为小脑半球、桥脑腹侧、小脑中脚和延髓橄榄的萎缩。某些异常信号 ,特别是桥横纤维的高信号在T2 和质子密度加权像上较易观察到更多还原

【Abstract】 Objective:To describe the clinical and MR features of olivopontocerebellar atrophy (OPCA).Methods::28 cases suspected OPCA clinically and confirmed by MRI were reviewed. All patients were evaluated with spin-echo sequence on 1.5T unit.Both T 1-weightcd.sagittal image and.T 1-,proton density,and T 2- weighted transversal images were available.Results:Volume losses of cerebellar hemisphere (n=28), ventral pons (n=28),middle cerebellar peduncles (n=28), and superior ventral medulla oblongata (n=26) were presented in almost all of the patients.T 2-and proton density weighted images often showed high-signaling of pontine transversal fibers(19/28) and middle cerebellar peduncles (12/28).Other signs such as midbrain and supratentorial abnormalities were also noted. Conclusion:MRI showed cerebellar hemisphere,ventral pons,middle cerebelllar peduncles and olive atrophies in OPCA patients.Abnormal intensities,especially hyperintensity of pontine transversal fibers were easily observed on T 2-and proton density weighted images.更多还原