【摘要】 对山东脐血库保存的 4 0 0 0人份脐血的部分结果进行了统计分析 ,每份脐血的平均有核细胞数超过 1.2× 10 9,每份脐血CD34+ 细胞总量平均为 3.9× 10 6,有 76 8人份脐血有核细胞数超过 1.5× 10 9,一般可满足体重 4 0kg以上的患者使用。对基因频率的分析表明 ,常见基因与中国其他地区的统计结果相近 ,有 4 0 %的患者可以在山东脐血库找到 1个位点不合的脐血更多还原

【Abstract】 The current study analyzed the data of 4 000 umbilical cord blood(UCB) units collected in Shandong Cord Blood Bank from the end of 1999 to March 2001. The averages of nucleated cells and CD34 + cells were more than 1.2×10 9 and 3.9×10 6 per UCB unit, respectively, and more than 1.5×10 9 nucleated cells per UCB unit were obtained in 768 UCB units. These UCB units are suitable for tansplantation in patients with a body weight greater than 40 kg. The analysis of HLA gene frequency showed that A2, A24, A11, B13, B51, DR15, DR7 and DR9 are the common halotypes in Shandong population and similar to those in the other areas of China. 40% patients could search out at least 1 UCB unit with 1 mismatched HLA locus in Shandong Cord Blood Bank.更多还原