【摘要】 目的　探讨老年恶性血液病患者医院感染的临床特点、发生原因及防治措施。方法　回顾分析 78例老年恶性血液病患者的院内感染发生率、危险因素、感染部位及治疗方法。结果　 78例中 42例 (5 3.8% )发生医院感染 ,高于同期非老年患者 (31 5 % )。危险因素为白细胞减少和化疗。感染部位以呼吸系统和口腔多见。感染病原菌主要为革兰阴性菌及真菌。结论　老年恶性血液病患者医院感染发生率高 ,疾病本身和化疗导致免疫抑制及骨髓抑制为医院感染的主要原因 ,经验性抗生素治疗及辅助治疗有利于控制感染更多还原

【Abstract】 Objectives To investigate the clinical features,causes and treatment of the hospital infection in the elderly patients with hematological malignant diseases. Methods The nosocomically infective rate,the risk factors, the most commonly infected sites and therapeutic methods of 78 elderly patients were analyzed retrospectively.Results The incidence of nosocomial infection in the senile patients(53.8%) was higher than that of non-senile patients(31.5%) in the corresponding period.The high-risk factors included low WBC and chemotherapy.The most commonly infected sites were respiratory system and oral cavity.The common pathogenic bacteria were mainly Gram-negative bacteria and funguses. Conclusions The nosocomially infective incidence of elderly patients with hematological malignant diseases is higher.The main causes were ossium medulla and immune inhibition,primary diseases and chemotherapy. Experience antibiotic treatment and supportive therapy may be good to control infection.更多还原