【摘要】 目的:探讨尿Na+/K+比值作为应用醛固酮拮抗剂螺内酯指标的可行性。方法:检测41例心功能Ⅲ～Ⅳ级病人的尿Na/K+比值,按比值的不同（<1.0或者>1.0）分两组,比较两组的治疗效果。结果:应用螺内酯后尿Na+/K+<1.0者受益大。结论:尿Na+/K+<1.0,可以作为使用螺内酯治疗心力衰竭的指标。更多还原

【Abstract】 Objective:To explore the feasible of using aldosterone antagonist according to urinary Na+/K+ ratio. Methods: Urinary Na+/K+ ratio was detected in 37 patients with congestive heart failure (CHF) before using spironolactone. Their heart function was NYHA grade Ⅲ-Ⅳ. According to urinary Na+/K+ ratio 37 patients were divided into group Ⅰ (Na+/K+ratio<1. 0, 21 cases) and groupⅡ (Na+/K+ratio***l. 0, 16 cases). Curative effectwas compared in 2 groups. Results: After using spironolactone, group Ⅰ patients got more benefit (F<0. 05) . Conclusion:Urinary Na+/K+ ratio <1. 0 is a good monitoring index when using spironolactone in CHF patents.更多还原