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磁共振扩散成像定量指标在脑缺血诊断中的应用

Study on MR-DWI quantitative analysis application in brain ischemia

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【作者】 王俭贾文霄木合拜提·马合苏提韩鸿宾

【Author】 WANG Jian, JIA Wen xiao, Muhebaiti, et al (Department of Image Center, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, China)

【机构】 新疆医科大学第一附属医院影像中心北京大学第三医院放射科 新疆乌鲁木齐830054新疆乌鲁木齐830054北京100083

【摘要】 目的:研究高扩散敏感梯度 (高 b值 )扩散加权像的定量指标在早期缺血性中风诊断中的应用 ,探讨高b值 DWI上异常高信号征象的诊断与鉴别诊断。 方法 :对 2 2 5例临床高度怀疑为缺血性中风的病例进行研究 ,对病灶进行表观扩散系数及其各向异性变异系数进行测定与计算 ,结合 ADC及其 CV对高 b值定性 DWI上异常高信号病灶进行分析 ,通过随诊或手术病理证实。结果:急性脑缺血病灶与其他假阳性病灶间的 ADC值及 CV之间存在统计学差异 (P<0 .0 5 )。 结论 :对急性期的假阳性病例 ,DWI的定量指标 ADC、CV等计算对疾病的诊断与鉴别诊断有价值 ,应列入常规

【Abstract】 Objective: To study the application of high b value diffusion weighted imaging(DWI) qualitative analysis for diagnosis of brain ischemic stroke. To investigate the differential diagnosis of the diseases. Methods: 225 cases which were highly suspected of brain ischemic stroke were studied.The study included analysis of the appearance of the lessions on DWI and measurement of apparent diffusion coefficient(ADC) values and anistropy(CV) as hyperintensity lesions on high b value DWI. The final diagnosis of the cases were verified by the following up examination or pathology. Results: ADC value was for the acute cerebral ischemic lesions was statistically different from that of the false positive cases (P<0.05). The CV between them was also statistically different with higher anistropy in false positive cases (P<0.05). Conclusion: ADC value and CV value should be calculated routinely as DWI quantitative analysis was used to make diagnosis.

  • 【文献出处】 新疆医科大学学报 ,Journal of Xinjiang Medical University , 编辑部邮箱 ,2002年03期
  • 【分类号】R743.3
  • 【被引频次】9
  • 【下载频次】101
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