【摘要】 目的:对驱虫斑鸠菊制剂的提取工艺进行优化。方法:采用 L1 6 (2 1 5)正交试验法 ,以黄酮总量为筛选指标 ,对提取工艺中影响因素进行考察 ;并对提取溶媒进一步优化。 结果 :提取溶媒对黄酮总量有显著性影响 (P <0 .0 5 )。驱虫斑鸠菊最适提取工艺为 80 %乙醇回流提取 3次 ,每次 6倍量溶媒 ,提取时间 1.5 h,提取液调 p H至7.5。结论:驱虫斑鸠菊优化工艺方法可行 ,可为制剂生产提供依据更多还原

【Abstract】 Objective: To study an optimum condition for extracting flavone ingredients in Vernonia Anthelmintica Willd. Methods: Using orthogonal design L 16 (2 15 ), influenced agents in extraction technique were deserved by detecting the content of total flavone ingredients and extraction solvent was chosen further. Results: Kinds of extraction solvents had significent influence on the content of total flavone ingredients (P<0.05). The optimum extraction process was as follows: adding 80% alcohol into materials and refluxing and extracting for 3 times, 1.5 hours every time, and adjusting pH to 7.5 in extraction solution. Conclusion: The optimal extraction technique which we offered is feasible in extraction of Vernonia Anthelmintica Willd and will be able to develop industrial scale according to this study.更多还原