【摘要】 目的　研究广东省青少年乳糖酶缺乏和乳糖不耐受的发生状况。方法　采用不同剂量乳糖进行氢呼气试验。按广东省地理分布 ,选择广州、珠海、佛山、韶关等 4个城市的 7～ 1 8岁健康中小学生 1 1 0 0名 ,摄入 2 5g乳糖后氢呼气试验阳性 (乳糖酶缺乏 )的 81 1人中 ,随机选取乳糖酶缺乏的青少年进行牛奶氢呼气试验。结果　随着乳糖摄入量的减少 (2 5g、1 2 .5g、6 .2 5g) ,乳糖酶缺乏的检出率均大幅度下降 ,分别为 73 .7%、1 9.7%、7.2 % ;乳糖不耐受的检出率亦有随着乳糖摄入量的减少而降低的趋势 ,检出率分别为 32 .9%、4 .3 %、2 .1 %。结论　广东省青少年乳糖耐受量为 6 .2 5g ,每次饮用奶 1 2 5ml,92 .8%的饮用者可以消化吸收 ,不致于出现不耐受症状更多还原

【Abstract】 Objective To find out the prevalence of lactase deficiency and lactose intolerance among juveniles in Guangdong province.Methods Lactose hydrogen breath test and cow milk hydrogen breath test were used to investigate the lactase deficiency and lactose intolerance. Based on the geographic distribution of Guangdong province, 1100 middle and primary school students, aged 7～18 years, were chosen from Guangzhou, Zhuhai, Fushan and Shaoguan cities. Cow milk hydrogen breath test were performed among juveniles who were drawn randomly from 811 students displayed positive results in hydrogen breath test (lactase deficiency) due to taking 25 grams of lactose. Results Prevalence of lactase deficiency (73.7%, 19.7% and 7.2%) and prevalence lactose intolerance (32.9%, 4.3% and 2.l%) decreased with the reduction in the lactase intake (25g, 12.5g, 6.25g) respectively. Conclusions The tolerance dose of lactose among juvenile in Guangdong province is 6.25 grams and 97.2% of the drinkers can digest and absorb 125ml of cow milk once without displaying symptoms of intolerance.更多还原