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定喘汤对哮喘发作患者TNF-α及IL-6的影响

Effects study of Dingchuantang on TNF - α and IL - 6 of asthma patients at stage of attack

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【作者】 简小云黄兆祺赖昕陈伟云

【Author】 Jian Xiaoyun , Huang Zhaoqi, Lai Xin , et al. Foshan Hospital of Traditional Chinese Medicine , Foshan 528000, Guangdong, China

【机构】 广东省佛山市中医院呼吸内科广东省佛山市中医院呼吸内科 528000528000528000528000

【摘要】 目的:探讨定喘汤对哮喘发作期患者TNF-α,IL-6的影响。方法:选择哮喘发作期患者48例,观察23例对照组(常规西医疗法)、25例观察组(常规西医疗法加定喘汤)治疗前后TNF-α,IL-6的变化水平。结果:观察组哮喘缓解时间快于对照组(P<0.05),观察组治疗后TNF-α,IL-6的降低水平明显优于对照组(P<0.05)。结论:哮喘发作期患者加用定喘汤治疗能明显降低TNF-α,IL-6分泌水平,缓解气道炎性反应。

【Abstract】 Objective: It is to discuss the effects of Dingchuantang on the TNF-α and IL- 6 of the asthma patients at stage of attack. Methods: Forty-eight patients with asthma at stage of attack were divided into control group and observation group. Twenty-three patients in the control group were treated with western medicine and twenty - five patients in the observation group were treated with western medicine and the Dingchuantang. The changes of TNF -α and IL-6 in both two group were respectively observed before and after treatment. Results: The relieving time in the observation group was shorter than that in the control group (P<0. 05). After treatment the levels of TNF -α and IL- 6 in the observation group were lower than that in the control group ( P < 0. 05 ). Conclusion: Based on western medicine, Dingchuantang can obviously decrease TNF-α and IL- 6 of asthma patient at stage of at-tack and relive the airway inflammation.

【关键词】 哮喘定喘汤TNF-αIL-6
【Key words】 asthma Dingchuantang TNF -α IL - 6
  • 【分类号】R259.622.5
  • 【被引频次】17
  • 【下载频次】130
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