【摘要】 为探讨低强度超声激活血卟啉对在体 S1 80肉瘤细胞的杀伤作用 ,对荷瘤小鼠采用声动力疗法处理 ,分别从癌组织生长状况、显微结构及超微结构等方面进行研究。结果表明 :超声激活血卟啉对肿瘤生长的抑制作用明显大于其他实验组 ,癌细胞在处理后的不同时间段 ,其显微结构及超微结构均表现出不同程度的损伤更多还原

【Abstract】 The antitumor effects of combined use of lower intensity ultrasound (US) and a photosensitizer, hematoporphyrin derivative(HpD) were determined in mice bearing sarcoma 180 by sonodynamic therapy(SDT). Antitumor effects were evaluated by investigating the tumors′ growing condition, microscopic structures and ultrastructures. The combined treatment with US and HpD showed remarkable synergistic effects on sarcoma 180.The structures of cancer cells showed various damages during different times.更多还原