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检测HM·CAP对幽门螺杆菌感染的诊断价值探讨

The diagnostic significance of measurement of the HM·CAP in H·pylori infection

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【作者】 沈江帆张乃康

【Author】 Shen Jiangfan, Zhang Naikang The Central Hospital of Putuo District, Shanghai 200062

【机构】 上海市普陀区中心医院上海市普陀区中心医院 上海200062上海200062

【摘要】 目的 探讨高分子量细胞相关蛋白 (Highmolecularweightcell-associatedprotein ,HM·CAP)对幽门螺杆菌 (Hp)的诊断价值。方法 对 40例正常人及 12 0例胃部疾病病人进行了HM·CAP检测 ,对其中 116例病人同时进行14 C -尿素酶呼吸试验 (UBT)、Hp培养及病理组织学对比。结果  40例正常人中 ,有 7例HM·CAP阳性 ,14 0例病人中 ,78例阳性。我们以14 C -UBT、Hp培养及病理组织学来评估HM·CAP对Hp的诊断价值 ,其敏感性分别为 97 4%、10 0 %、97 3 % ,特异性为 94 7%、74 5 %、90 % ,诊断符合率为96 6%、88 8%、94 8%。结论 HM·CAP是一种具有较高敏感性及特异性的诊断Hp感染的方法。

【Abstract】 Aim To measure the HM·CAP to detect Hp infection. Methods 40 controls and 120 patients with symptoms of epigastric pain were measured by the HM·CAP and compared with 14 C-UBT, Hp culture and histology. Results Sera of 7 cases of the 40 controls and 78 cases of the 120 pateints were positive for HM·CAP. The detection of HM·CAP were compared with 14 C-UBT,Hp culture and histology. Their senstitivities were 97.4%, 100%, 97.3%, specificities were 94.7%,74.5%,90.0% and conincidence rates were 96.6%?88.8%?94.8% compared with 14 C-UBT, Hp culture and histology, respectively. Conclusion HM·CAP measurement is a sensitive and specific detection of Hp infection.

  • 【文献出处】 胃肠病学和肝病学杂志 ,Chinese Journal of Gastroenterology and Hepatology , 编辑部邮箱 ,2002年01期
  • 【分类号】R817.4
  • 【下载频次】14
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