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木瓜粉对缺血性脑梗塞患者血中丙二醛和超氧化物歧化酶的影响

The effect of Bio-Normalizer (BN) on blood MDA and SOD of patients with ischemic cerebral infarction

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【作者】 康静黄国伟石雁川常红任大林

【Author】 KANG Jing,HUANG Guo-wei,SHI Yan-chuan,CHANG Hong,REN Da-lin(College of Public Health, Tianjin Medical University, Tianjin 300070,China)

【机构】 天津医科大学公共卫生学院天津医科大学公共卫生学院 天津300070天津300070天津300070

【摘要】 目的 :观察木瓜粉 (BN)对缺血性脑梗塞患者血清中丙二醛 (MDA)和红细胞中超氧化物岐化酶 (SOD)的影响。方法 :选取年龄为50~70岁的缺血性脑梗塞病人 ,将其分为3组 :急性期、恢复期和对照组。每组均为30例。抽取清晨空腹血于实验开始第一天、第二周末和两个月末共3次 ,进行抗氧化指标MDA、SOD的测定。结果 :急性期、恢复期实验后MDA低于实验前和实验中的MDA ,其中急性期差异有显著性 (P<0.05) ,恢复期差异无显著性。急性期、恢复期实验后SOD活性高于实验前和实验中SOD活性。结论 :BN具有较强的抗氧化能力 ,能够提高脑梗塞患者血中SOD活性 ,降低脂质过氧化产物MDA含量

【Abstract】 Objective:To observe the effect of BN on serum MDA and SOD of patients with ischemic cerebral infarction.Methods: The patients with ischemic cerebral infarction aged 50~70.They were divided into 3 groups: acute, recovery and control groups. There were 30 patients in every group. The fasting blood was picked in the lst day ,the 2nd week and the end of the 2nd month, respectively.The serum MDA content and RBC SOD activity were detected. Results: The serum MDA content after experiment was lower than that before experiment in acute and recovery groups. There was significant difference in acute group (P<0.05), but not in recovery group.The RBC SOD activity after experiment was higher than that before and middle experiment in acute recovery groups.Conclusion: BN had antioxidant properties which can increase the activity of SOD in blood of the patients with ischemic cerebral infarction and decrease the content of lipid peroxidant MDA.

【关键词】 木瓜粉抗氧化脑梗塞MDASOD
【Key words】 PapayaAntioxidationCerebral infarctionMDASOD
【基金】 中日国际合作课题
  • 【文献出处】 天津医科大学学报 ,Journal of Tianjin Medical University , 编辑部邮箱 ,2002年02期
  • 【分类号】R743.33
  • 【被引频次】3
  • 【下载频次】61
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