【摘要】 目的 :观察卡孕栓、米索前列醇、缩宫素 ,分别用于预防剖宫产术出血的临床效果。方法 :选择 2 30例足月未临产的产妇 ,随机分为 3组 ,卡孕栓组 75例 ,米索组 79例 ,均在打开腹膜时舌下含服卡孕栓 1枚或米索 4 0 0μg;缩宫素组 76例 ,术中娩胎儿时静脉点滴缩宫素 2 0 U,胎儿娩出后即刻向宫体肌注缩宫素 30 U,观察各组术中及术后 2小时内出血量。结果 :术中及术后 2小时内平均出血量 :卡孕栓组 (2 2 3± 5 5 .6 ) ml,米索组 (2 14± 5 4 .5 ) ml,缩宫素组(372± 6 0 .7) ml,卡孕栓组与米索组比较 ,差异无显著性 (P >0 .0 5 ) ;卡孕栓组、米索组与缩宫素组比较 ,差异均有非常显著性 (P<0 .0 1)。结论 :卡孕栓与米索促进子宫收缩作用强于缩宫素 ,能较好地预防产后出血 ,且用药安全 ,检查方便 ,副作用小。更多还原

【Abstract】 Objective:To observe the effects of methyl carprost,misopro stol ,oxytocin on reduction of postpartum bleeding in cesarean section . Methods: Having chosen 246 full term but not parturient lyin gin women, randomize them into three groups, 75 lying in women taking menthyl carprost and 79 lying in women taking misoprostol ,when peritoneum was incised, Every lying in women in above mentioned tow groups takes a piece of methyl carprost or misoprostol 400 μg respectively.76 lying in women take oxytocin 20 IU oxytocin intravenous injection and 30 IU oxytocin injected into uterine muscle immediately after delivery of baby, observe the amount of bleeding within two hours after delivery respectively. Result:the overage the amount of bleeding within two thours after delivery is measured:Methyl carpost group (223±55.6) ml. Misoprostol group (214±54.5) ml.Oxytocin group (372±60.7) ml.The difference is unobvious P>0.05 between methyl carpost group and misoprostol group.And it is unobvious P<0.01 between methyl carpost group,misopostol group and xoytocen group.Conclusion:methyl carpost or misoprostol is better than oxgtocin in promoting uterine contraction. Methyl carprost and misoprostol can prevent postpartum bleeding dffectively,moreover they are safe and convenient take with little side effect.更多还原