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固定白蛋白膜促进传递机理的研究
Preparation of BSA-Filled Facilitated Transport Membrane and Analyzing the Facilitated Transport Mechanism
【摘要】 以聚砜为原料制得非对称多孔指状超滤膜 ,将白蛋白固定于该膜中制得了固定白蛋白促进传递膜 .经实验验证 ,应用该膜清除亲脂性毒物胆红素明显优于空白膜 .通过对清除过程传递机理的分析 ,建立了膜中固定载体促进传递的数学模型 ,获得了模型参数及其数值解 ,且通过促进因子 F的理论值与实验值的比较 ,验证了模型的正确性
【Abstract】 The BSA filled facilitated transport ultrafiltration membrane is prepared by filling albumin into the unsymmetrical finger like polysulfone membrane. Experiments demonstrate that it can well remove the lipophilic toxins, bilirubin. By analyzing the facilitated transport mechanism, a mathematical model is proposed and the numerical solution as well as the model parameters are obtained.It shows that the model predictions are in good agreement with the experimental data by studying the facilitated factor F.
【关键词】 白蛋白;
胆红素;
促进传递;
膜分离;
聚砜膜;
【Key words】 albumin; bilirubin; facilitated transport; membrane separation; polysulfone membrane;
【Key words】 albumin; bilirubin; facilitated transport; membrane separation; polysulfone membrane;
【基金】 国家自然科学基金资助项目 (2 97760 36)
- 【文献出处】 天津大学学报 ,Journal of Tianjin University , 编辑部邮箱 ,2002年02期
- 【分类号】TQ028.8
- 【下载频次】71