【摘要】 优化了聚酰胺胺树形分子合成工艺条件 ,采用HPLC和热重分析 (TG)相结合的方法对所合成的树形聚酰胺胺进行分析与表征 ;HPLC的分析表明 ,在各不同代的目标化合物中 ,均有反应物单体存在 ,在高代产物中除了含有少量反应物外 ,还有少量的低代数分子 ;TG分析表明 ,产物中小分子反应物占的比例很少 ,一般为2 %～3 %左右 ,如果将减压蒸馏后的产物重新进行真空干燥 ,对半代树形大分子 ,能进一步有效除去小分子反应物 ,而对于整数代树形大分子 ,则效果并不理想更多还原

【Abstract】 To optimize the conditions for polyamidoamine(PAMAM) dendrimer synthesis, reverse _ phase HPLC and TGA were used for the characterization of polymers. The HPLC analytical results indicated that the target products of higher generations contained products of lower generations as well as monomers. TGA results showed the presence of 2%～3% reactants in PAMAM dendrimers. Macromolecular half _ generation dendrimers could be purified by vacuum drying at 50 ℃ and 267 Pa after distillation under reduced pressure. However, such treatment is not very effective for dendrimers of full generations.更多还原