【摘要】 本文对深圳市 1992～ 2 0 0 1年报告的 12 9例急性弛缓性麻痹 (AFP)病例及标本监测结果进行分析 ,结果显示 ,发病年龄主要集中在 3岁以下儿童 ,男性多于女性 ;发病时间和地区分散 ,无明显季节性和地区聚集性 ;17.83 %病例无免疫史 ;2 5 .5 8%病例 60 d随访仍残留麻痹。 12 4例粪便标本 ,分离出非脊灰肠病毒 17例 ,脊灰病毒 2 2例 ;其中 1992～1993年 4例为脊灰野毒株 ,1994～ 2 0 0 1年 18例为脊灰疫苗株。检出 18例脊灰疫苗株中 ,4例为疫苗相关病例 (VAPP) ,VAPP发生率为 0 .90 /10 0万。另有 6例疑似疫苗接触者相关病例 ,其特点是 :1无免疫史 ,接触史不明 ;2病例分散分布 ;3临床特征有发热 ,非对称性弛缓性麻痹 ;4发病 60 d后仍残留麻痹更多还原

【Abstract】 Objective Analyze the AFP Cases in Shenzhen in 1992～2001. No obvious gathering phenomenon of the cases was seen. 17.83% of them were non-vaccinated. 25.58% of them were residue paralysis. Method 22 cases of poliovirus and 17 cases of non-poliovirus were isolated for the detection sample in 124 Cases. Result In the 22 cases of poliovirus, 4 cases were wild poliovirus and 18 cases were vaccine-derived poliovirus. In the 18 cases vaccine-derived poliovirus, 4 cases were vaccine associated paralytic poliomyelitis. It is estimated that the general incidence of VAPP was 0.90/1000000. The other 6 cases were suspected to be contact vaccine associated paralytic poliomyelitits. The result showed that all cases occurred in 0～3 yeas old, the male was more than the female. Conclusion Their characteristics were:①Cases were non-vaccinated and non-contact;②cases were dispersely distributed;③Clinical symptoms were fever, asymmetrical flaccid paralysis and were diagnosed as poliomyelitis climically;④Residue paralysis was seen 60 days after disease onset.更多还原