【摘要】 目的 :探讨超声心动图 (UCG)对强直性脊柱炎 (AS)心脏损害的评估价值。方法 :32例不伴有心血管表现 AS患者进行 U CG检查 ,观察心脏形态学、血流动力学和心室舒张功能改变。结果 :6 8.8%出现主动脉弹性减退 ,2 1.9%出现主动脉根部增厚或扩张。4 6 .8%出现瓣膜关闭不全 ,其中主动脉瓣关闭不全发生率为 2 5 .0 %。二尖瓣关闭不全发生率 15 .6 %。三尖瓣及肺动脉瓣轻微关闭不全各占 3.1%。AS患者左室流出道内径、室间隔厚度及主动脉根宽度较正常对照组高 (P<0 .0 5或 0 .0 1) ,舒张功能下降。结论 :UCG有助早期发现 AS心脏损害更多还原

【Abstract】 Objective To explore the significance of ultrasonic cardiographic (UCG) examination for heart injury in patients with ankylosing spondylitis (AS). Methods 32 AS patients without clinical evidence of cardiovascular disease and 30 age and gender matched healthy people (control group) underwent UCG examination, changes of the cardial structure and function of valves, myocardial function of left ventricle and the pericardium were assessed. Results Aortic spring declining and aortic root thinkening/dilatation were seen in 68.8% and 21.9% of patients respectively, including regurgitation of aortic valve (25%), mitral valve (15.6%), tricuspid valve (3.1%) and pulmonic valve (3.1%). Intradiameter of left ventricular outflow tract, thickness of interventricular septum and width of aortic root were higher in AS patients than these in control group. It was found that diastolic function of the left ventricle was descending in patients with AS. Conclusion UCG examination is helpful for finding cardia impairment early in AS patients.更多还原