节点文献

抗病毒无菌粉针剂抗病毒作用的研究

Studies on the antivirus effect of antivirus powder injections

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 张国刚宋少江徐绥绪张红霞段淑敏李晓红

【Author】 ZHANG Guo gang 1, SONG Shao jiang 1, XU Sui xu 1, ZHANG Hong xia 1, DUAN Shu min 2, LI Xiao hong 3 (1 School of Traditional Materia Medica,Shenyang Pharmaceutical University, Shenyang 110016,China; 2 Institute of Virology,Chinese Academy of Preventive Medicine, Beijing 100052,China; 3 Liaoning Province Mother and Children Health Care Hospital,Shenyang 110005,China)

【机构】 沈阳药科大学中药学院中国预防医学科学院病毒研究所辽宁省妇幼保健院 辽宁沈阳110016辽宁沈阳110016北京100052辽宁沈阳110005

【摘要】 目的为明确抗病毒粉针剂体内外抗病毒谱及作用机制。方法采用组织细胞培养法、MTT染色法 ,检测抗病毒粉针剂对不同病毒株的作用 ,通过改变给药时间、途径 ,探讨抗病毒粉针剂抗病毒作用环节。通过建立病毒性流感动物模型 ,采用组织病理学检查法 ,观察抗病毒粉针剂对感染动物的保护作用。结果抗病毒粉针剂具有明显的抗流感病毒、呼吸道合胞病毒、腺病毒的作用 ,抗病毒作用是多途径的。结论抗病毒粉针剂是一个较广谱的抗呼吸道病毒针剂

【Abstract】 Objective To expound antivirus spectra and the mechanism of the antiviral action of the antivirus powder injections (API).Methods To observe the inhibition of various viruses by API,the methods of the tissue culture,the cell culture as well as the MTT dye absorption test were used The antiviral effect of the API was studied by using the API with different administration procedures and routes.The animal models of pneumonia were made and the protection of the API in the animals was observed.Results The API had significant antivirus effect against the influenza viruses,respiratory syncytial viruses and adenoviruses.Conclusions The API is a wide spectrum antivirus medicine and has various antiviral mechanisms.

  • 【文献出处】 沈阳药科大学学报 ,Journal of Shenyang Pharmaceutical University , 编辑部邮箱 ,2002年06期
  • 【分类号】R285
  • 【被引频次】13
  • 【下载频次】132
节点文献中: 

本文链接的文献网络图示:

本文的引文网络