【摘要】 目的　研究老年人睡眠呼吸暂停综合征 (SAS)与代谢综合征 (MS)之间的关系。　 方法 　分别对 2 9例轻、中度 ,2 0例老年重度SAS患者及 3 2例无SAS的对照者进行血压 (BP)、体质量指数 (BMI)、空腹血糖 (FBG)、血清胰岛素 (INS)、甘油三酯 (TG)、总胆固醇 (TC)、低密度脂蛋白 (LDL)、高密度脂蛋白 (HDL)及尿酸 (UA)测定。　 结果　轻、中度与重度SAS组各参数测定结果与对照组存在显著性差异 (P <0 0 5～ 0 0 1)。而重度SAS组与对照组结果差异非常显著 (P <0 0 1)。　 结论 　睡眠呼吸暂停患者较正常者更易发生代谢紊乱 ,导致MS的产生。重度SAS患者发生代谢紊乱的程度更为严重。更多还原

【Abstract】 Objective To investigate the relationship between sleep apnea syndrome(SAS) and metabolic syndrome(MS) in the aged. Methods Blood pressure(BP)?body mass index(BMI)?fasting blood glucose(FBG)?serum insulin(INS)?triglyceride(TG)?total cholesterol(TC)?low density lipoprotein(LDL)?high density lipoprotein(HDL) and uric acid(UA) were measured in 49 patients with SAS and 32 normal controls. Results BMI?SBP?DBP?FBG?INS?TG?TC?LDL and UA were higher in patients with SAS than those in normal controls.ISI and HDL were lower in patients with SAS than those in normal controls( P <0 05～0 01) There was significant difference between severe SAS group and normal group in the parameters above( P <0 01) Conclusions Patients with sleep apnea can have metabolism disorder more easily than normal subjects and eventually metabolism syndrome comes up.Patients with severe SAS have more severe metabolism disorder.更多还原