【摘要】 重复 DNA序列是细菌基因组中的一个重要组成部分 ,而 ERIC(IRU )序列是在肠道细菌基因组中发现的一类基因间重复序列。本研究使用 HMMER软件建立 ERIC序列族的模型 ,并用该模型对 4 6个已测序的菌株进行全基因组序列搜索 ,并对搜索结果进行比较分析 ,找出 ERIC(IRU )序列在不同细菌基因组中的分布规律 ,即 ERIC序列主要存在于肠道细菌中 ,并不是在细菌基因组中普遍存在的更多还原

【Abstract】 Repetitive DNA sequence is an important component in bacterial genomes,and ERIC(Enterobacterial Repetive Intergenic Consensus)(IRU) (Intergenic Repetive Unit) sequence is a kind of intergenic repetitive sequence found in enterobacterium.The profile model of ERIC sequence family was built by using the HMMER software package and whole genome sequences of 46 bacteria were searched by the model.Based on the statistics and analysis of genome search results,some rules about the distribution of ERIC(IRU) in bacteria genomes was got:ERIC sequences existed mainly in enterobacterium rather than universally in bacterial genomes.更多还原