【摘要】 基因打靶是近年来发展起来的对细胞基因组中的某一基因进行定点操作的生物技术。综述了基因打靶的筛选系统 ,影响基因打靶效率的几个主要因素及其解决方法 ,总结了基因打靶在各个学科领域中的应用。更多还原

【Abstract】 Gene targeting is a kind of main developing bio-technique recently to operate a simple gene in cellular genome precisely. The article illustrates gene targeting selection systems, analyses several main factors which affect the efficiency of gene targeting, provides some strategies to solve those problems and reviews the applications of gene targeting in many fields.更多还原