节点文献
后基因组时代药理学研究趋向
Trends in the Post-genomic Pharmacological Research
【摘要】 药理基因组学 (药物基因组学 ,pharmacogenomics)将成为后基因组时代药理学研究的新领域。与此相应 ,高通量筛选 (high throughputscreening ,HTS)、insilico研究以及多种功能可视化技术已开始成为药理学研究的新方法。本文同时介绍上述新思路与新方法应用于药效学、药动学研究的某些进展
【Abstract】 With the advent of post genome era, pharmacogenomics will be a new field in pharmacological sciences. In parallel, high throughput screening, in silico research, as well as lots of visualization techniques are emerging as novel approaches in pharmacological researches. Some progress in the implementation of aforementioned new idea and methods in pharmacodynamics and pharmacokinetics research are also introduced in this review.
【关键词】 药理基因组学;
高通量筛选;
药效学;
药动学;
【Key words】 Pharmacogenomics; High throughput screening; Pharmacodynamics; Pharmacokinetics;
【Key words】 Pharmacogenomics; High throughput screening; Pharmacodynamics; Pharmacokinetics;
【基金】 国家重点基础研究发展规划 (973)项目G19990 5 40 0 3子课题资助
- 【文献出处】 生理科学进展 ,Progress In Physiological Sciences , 编辑部邮箱 ,2002年01期
- 【分类号】R965
- 【被引频次】6
- 【下载频次】168