【摘要】 目的　探讨血清甘氨酰脯氨酸二肽氨基肽酶 (GPDA)对胃癌的诊断价值。方法　采用速率法在OLYMPUSAU 10 0 0全自动生化分析仪上对 31例胃癌术前患者 ,2 7例胃切除术后患者 ,30例胃良性疾病患者及 30名正常人进行了血清GPDA的活性测定 ,对 31例胃癌术前患者与 2 7例胃切除术后患者GPDA的含量进行了对比分析。结果　显示GPDA对胃癌的诊断敏感性为 71.0 % ,特异性达 93.3%。肿瘤病灶去除后 ,GPDA活力有升高趋势。结论　GPDA活力测定在胃癌的诊断、普查筛选及术后随访中有一定的实用价值更多还原

【Abstract】 Objective To observe the diagnositic value of glycyl proline dipeptidyl aminopeptidase (GPDA) in gastric cancer. Method GPDA activities in 31 patients with gastric cancer before surgery, 27 patients of gastric cancer after surgery, 30 patients of benign gastric disease and 30 normal people were tested by rate method assays with OLYMPUS AU 1000 instrument. Results Results showed that the diagnositic sensitivity of GPDA was 71.0%, GPDA activities trended to rise after the tumor was removed. Conclusion GPDA assay not only had practical value in the diagnosis and screening of the gastric cancer, but also had practical value in following up the gastric cancer patients after surgery.更多还原