【摘要】 目的 了解晚发与早发精神分裂症临床症状之间的差异。方法 对不同年龄初发精神分裂症患者进行BPRS、SANS、SAPS、HAMA和HAMD量表评定,然后作临床症状的比较。结果 晚发组在BPRS缺乏活力因子分,SANS总分,HAMD迟缓、绝望感因子分低于早发组,BPRS敌对猜疑因子分高于早发组(P<0.05)。晚发组的以被害妄想、牵连观念、情绪不稳较多见,而被洞悉感、思维形式障碍、情感迟钝、意志缺乏较少。结论 晚发精神分裂症与早发精神分裂症的临床症状有所不同,提示晚发精神分裂症可以作为精神分裂症的一个亚型。更多还原

【Abstract】 Objective To detect the differences of clinical symptoms between late-onset and early-onset schizophreni-a. Methods Different ages of patients with schizophrenia who were first-onset were assessed by the BPRS, SANS, SAPS, HAMA and HAMD. Their clinical symptoms were compared. Results The scores of SANS, factor of lack of activity in the BPRS and factors of tardy, feeling of despair in the HAMD were lower in the late-onset group, but the score of hostile-suspicious factor in the BPRS was higher than that of the early-onset group (p < 0.05) .Delusion of persecution,idea of reference and emotional lability in the late-onset group were seen more often than early-onset one, but, mind reading, thought disturbance , emotional blunting and abulia were less in the former. Conclusion Late-onset schizophrenia which might be a subtype of schizophrenia is different from early-onset one in clinical symptoms.更多还原