【摘要】 【目的】探讨以健脾补肾为主、佐以化瘀祛浊中药组成的康肾片对慢性肾衰维持血透患者的治疗作用。【方法】 80例慢性肾衰维持血透患者随机分成康肾片治疗组 (简称中药组 )和单纯血透治疗对照组 (简称对照组 ) ,两组在对症处理相同、血透相关因素一致条件下维持血透治疗 ,中药治疗组同时服用康肾片。系统观察两组患者血肌酐 (SCr)和血尿素氮(BUN)水平、平均每周透析次数、透析充分性、营养状况、细胞免疫功能、透析生存率、电解质等方面的变化。【结果】中药组比对照组SCr、BUN均降低 (P <0 0 1) ,平均每周透析次数减少 (P <0 0 5 ) ,长期透析充分性提高 (P <0 0 1) ,营养指标改善 (P <0 0 1) ,高磷状态降低 (P <0 0 1) ,细胞免疫功能提高 (P <0 0 1)。透析生存率延长 (P <0 0 1或P <0 0 5 )。【结论】康肾片治疗慢性肾衰维持血透患者 ,具有提高患者长期透析充分性和减少透析次数 ,提高细胞免疫功能 ,改善患者营养状况及高磷状态 ,提高患者透析生存率等作用。更多还原

【Abstract】 To explore the synergistic action of Kangshen Tablet (KT), which has the functions of nourishing kidney, invigorating spleen, eliminating stasis and turbidity, in maintenance hemodialysis for chronic renal failure (CRF).Eighty cases of CRF were randomly allocated to Group A (maintenance hemodialysis alone) and Group B (KT combined with maintenance hemodialysis).Serum creatine (SCr) and blood urea nitrogen (BUN) levels, average times of hemodialysis per week, adequacy of hemodialysis, nutrition status, cellular immune function, survival rate and serum electrolyte levels were observed.After treatment, SCr and BUN levels were decreased, average times of hemodialysis per week reduced, adequacy of hemodialysis raised, nutrition status improved, cellular immune function promoted, survival rate increased and hyperphospheremia decreased in Group B (P<0 01 or P<0 05 as compared with Group A).[Conclusion]KT exerts a good synergistic action in maintenance hemodialysis for CRF.更多还原