【摘要】 目的 分析三亚食盐加碘前后甲状腺机能亢进症发病变化及影响因素。方法 采用临床病例分析、流行病学调查、病例对照研究、环境及居民碘营养水平分析。结果 甲亢患病率为2.59‰,沿海、丘陵、山区无显著性差异。加碘前甲亢住院病例稳定在24.2～30.4/10万,加碘后逐年上升,1998年达到高峰后又逐年下降至加碘前水平。病例对照发现家庭收入、食碘盐、海产品、家庭生活事件、感染为危险因素。水碘均值为14.81μg/L,尿碘中位数在87.07～235.8μg/L之间。结论　全民食盐加碘后造成碘性甲亢的发生是存在的,但是暂时性的,非持续性的。部分户碘盐含碘量过高也会诱发碘性甲亢的发生。更多还原

【Abstract】 Objective To analyze the status of hyperthyroidism and the factors affecting the disease before and after addition of iodine in the common salt in Sanya City. Methods Case - control study was carried out for clinical analysis of cases with hyperthyroidism and factors of environment and the status of iodine nutrtionin in the inhabitans were also investigated. Results The results show that the incidence of hyprethyroidism was 2.59‰ and there were no differences in the coastal, hilly and mountainous areas. The incidence of hyperthyroidism before taking the iodine-containing salt was maintained at 24.2- 30.4 per 100 000, and increased after taking iodine - containing salt year by year, the incidence reached its peak in 1998 and then decreased year by year to the level before addition of iodine into common slat. The family income, condition of taking iodine - containing salt and sea products, other infections might be the risk factors.lt was also observed that the mean value of iodine in the water was 14.81μg/L,the median of iodine in the uring was between 87.07 -235.8μg/L.Conclusion Massive taking the iodine- containing salt might resulted in the occurrence of hyperthyroidism,though it was temporarily and occasionally occurred.更多还原