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269例大肠癌病例对照研究

Case-control Studies of 269 Cases with Colon Cancer

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【作者】 张振亚赵泽贞马志强李春仲

【Author】 ZHANG Zhen ya,ZHAO Ze zhen,MA Zhi qiang,et al.Department of Surgery,Hebei Tumor Hospital,Shijiazhuang 050011,China

【机构】 河北省肿瘤医院外二科河北省肿瘤研究所流行病学室河北省肿瘤医院外二科 河北石家庄050011河北石家庄050011河北石家庄050011

【摘要】 目的 :通过对大肠癌患者进行回顾性研究 ,力求寻找大肠癌发病的相关因素。方法 :运用 1∶1病例对照研究方法 ,对 2 6 9例大肠癌的相关因素进行调查 ,其数据分别用EPI软件及SAS软件处理。结果 :分析结果显示肠道既往病史、鱼肉和蛋类高蛋白食品摄入过多为大肠癌的相关危险因素 ;而足量蔬菜摄入则为大肠癌的相关保护因素。单因素分析结果还显示大便情况异常、蔬菜烹调过熟、精神创伤史、消化道用药史可能与大肠癌有关联。肿瘤家族史、吸烟、饮酒、饮茶、水果、奶制品、肥肉以及油炸食品摄入与大肠癌的发病未显示统计学联系或关联强度不大。结论 :本研究显示通过降低肠道疾病发生、减少高蛋白食物摄入和多食新鲜蔬菜有助于预防大肠癌的发生。

【Abstract】 Objective To search the relative factors for occurence of the colon cancer.Metheds 269 cases in 1∶1 paired case control were studied.the data was input the computer and handled by EPI software and SAS software.Results History of intesttional disease,over intake of fish and eggs are correlative risk factors of colon cancer,ample intake of regetables is a correlative protection factor.Single factor analysis showed that abnormality of defecation,over cooking of regetable,psychological trauma,medication history of digestive duct are probably correlative with colon cancer.There is not or not strongly correlative between incidence of colon cancer and following factor:family history of cancer,smoking,consumption of alchohol,tea,fruits and milkproducts,over intake of fat and fried food.Concusions Reducing the occurrance of intestinal disease,intake less protein,and enough fresh vegetable can profit to prevent colon cancer.

  • 【文献出处】 肿瘤防治杂志 ,Journal of Qilu Oncology , 编辑部邮箱 ,2002年06期
  • 【分类号】R735.34
  • 【被引频次】9
  • 【下载频次】170
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