【摘要】 综述了应用核磁共振测定有机化合物绝对构型的各种方法 .根据方法的原理 ,将方法分为两类 ,一类是应用芳环抗磁屏蔽效应测定有机化合物绝对构型的NMR方法 ,包括Mosher法 ,改进的Mosher法 ,MPA以及其他AMAs手性试剂方法 ;另一类是应用配糖位移效应测定有机化合物绝对构型的NMR方法 ,包括 4 O 苯甲酰基葡萄吡喃糖甙方法和岩藻呋喃糖甙方法等 .本综述包括各种方法的原理 ,测定绝对构型的步骤等更多还原

【Abstract】 This paper reviews the NMR methods to determine the absolute stereochemistry of organic compounds.The methods are classified into two types in terms of the principle in this paper. One applies magnetic anisotropy effect of phenyl or other aryl groups, such as Mosher method, methods utilizing MPA or other AMAs chiral reagents. The other type applies glycosylation shift effects due to glycosylate reactions, such as tetra O benzoyl glucosylation method and fucofuranoside method. This review deals with the principle, the determining process, the advantages and disadvantages of each mothod.更多还原