【摘要】 目的 :观察Ⅱ型糖尿病患者血清中谷氨酸脱羧酶抗体与胰岛素、C -肽水平之间的关系。方法 :检测78例Ⅱ型糖尿病患者的血清GAD -Ab水平以及胰岛素及C肽释放试验等项目。结果 :78例糖尿病患者中有 30例GAD -Ab阳性 ,阳性率为 38.4%;GAD -Ab阳性组患者与阴性组患者相比较 ,平均年龄、空腹血糖、空腹及餐后 2小时胰岛素、C肽水平均有明显差异 ,但餐后 2小时血糖水平差异不显著。结论 :Ⅱ型糖尿病患者也存在着较高的GAD -Ab阳性率 ;GAD -Ab阳性患者的胰岛素、C -肽水平低。更多还原

【Abstract】 Objective:to observe the relationship between Glutamic acid decarboxylase (GAD) antibody and the insrlin, C-peptide levels in typeⅡdiavetic patients.Methods:Wedetected the serum conentratlion of theGlutamic acid decarboxylase antibody and the insulin,C-peptide in 78 type Ⅱdiabetic patients.Results:the positive rate of the Glutamic acid decarboxylase was 38.4%(30/78);In compare with the patients whose Glutamic acid decarboxylase antibody were negative, the concentration o finsulin and C-peptide in serum was lower in these patients.Conclusion:the positive rate of the Glutamec acid decarboxylaseantibody was still high in type Ⅱdiabetic patients in compare with typeⅠ,and the comcentration of insulin and C-peptide in serum was lower in these patients.更多还原