【摘要】 衰老是细胞生命活动的基本规律之一,通常是一个渐进而复杂的细胞生理与生化反应过程。细胞衰老的发展过程与线粒体形态结构、功能有着密切关系。在袁老过程中,线粒体生物学、生理学、分子生物学方面都发生变化,线粒体产生自由基,而自由基对线粒体的损伤对衰老的发展起到促进作用;线粒体DNA突变对细胞衰老的进程有密切联系。更多还原

【Abstract】 Senescence is one of the fundamentals of cellular vital motion, which is usually a gradual and intricate process of cellular physiologic and biochemical reaction. Cellular senescence is closely related to the morphic, structure and functions of the mitochondrion. In this process, mitochondrion has many changes in biology, physiology and moleculeology. Mitochondrion generates free radical which damages itself and gradually promotes itself senescence. MtD-NA mutation also promotes itself senescence.更多还原