【摘要】 目的　了解糖尿病患者尿中 5种微量蛋白与其病程的关系。方法　用Beckman的Arrray36 0特定蛋白散射仪测定 75例 2型糖尿病患者 (2 DM )尿中的免疫球蛋白G(IgG)、白蛋白 (Alb)、α1 微球蛋白(α1M )、β2 微球蛋白 (β2 M )和转铁蛋白 (TRF)。结果　随着糖尿病病程的进展 ,尿中 5种微量蛋白除 β2 M外均有显著升高 (P <0 0 5和P <0 0 1) ,α1M最为显著。结论　尿中微量蛋白可作为糖尿病肾病 (DN)早期诊断的敏感指标。更多还原

【Abstract】 Objective To investigation the relationship between five kinds of urinary microprotein and the course of disease in diabetics.Methods The levels of urinary immnuglobulin G（IgG）,albumin（Alb）,α₁-microglobulin（α₁M）,β₂-microglobulin（β₂M）,and transferrin（TRF） in 75 cases of the patients with type 2-diabetes were examined by nephelometry.Results With development of the course of disease,five kinds of urinary microprotein,except β₂M,increased significantly（P<0.01 and P<0.05）,and α₁M especially does.Conclusion Urinary microprotein can be regarded as sensitive indexes for early diagnosis of diabetic nephropathy.更多还原